rs2660753
| Orientation | plus |
| Stabilized | plus |
| Make rs2660753(C;C) |
| Make rs2660753(C;T) |
| Make rs2660753(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 3 |
| Position | 87061524 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2660753 |
| dbSNP (classic) | rs2660753 |
| ClinGen | rs2660753 |
| ebi | rs2660753 |
| HLI | rs2660753 |
| Exac | rs2660753 |
| Gnomad | rs2660753 |
| Varsome | rs2660753 |
| LitVar | rs2660753 |
| Map | rs2660753 |
| PheGenI | rs2660753 |
| Biobank | rs2660753 |
| 1000 genomes | rs2660753 |
| hgdp | rs2660753 |
| ensembl | rs2660753 |
| geneview | rs2660753 |
| scholar | rs2660753 |
| rs2660753 | |
| pharmgkb | rs2660753 |
| gwascentral | rs2660753 |
| openSNP | rs2660753 |
| 23andMe | rs2660753 |
| SNPshot | rs2660753 |
| SNPdbe | rs2660753 |
| MSV3d | rs2660753 |
| GWAS Ctlg | rs2660753 |
| GMAF | 0.2681 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
cancer-genetics these snps influence genetic risk for prostate cancer
[PMID 18708398
] rs2660753 showed a per-allele OR, 1.08 (95% confidence interval, 1.00-1.16; P = 0.06)
An initial report [PMID 18974127] of an association with between this SNP and risk for ovarian cancer was not replicated when the same authors expanded the study over 12 studies comprising 4,482 cases (and over 6,000 controls).[PMID 21415361]
[PMID 19336566] Replication of the 10q11 and Xp11 Prostate Cancer Risk Variants: Results from a Utah Pedigree-Based Study.
| GWAS snp | |
|---|---|
| PMID | [PMID 18264097] |
| Trait | Prostate cancer |
| Title | Multiple newly identified loci associated with prostate cancer susceptibility |
| Risk Allele | T |
| P-val | 2.9999999999999997E-8 |
| Odds Ratio | 1.18 [1.06-1.31] |
[PMID 21898988] [Two single nucleotide polymorphisms on chromosome 3 and the risk of prostate cancer in Chinese men]
[PMID 22549899] Genetic polymorphism and prostate cancer aggressiveness: A case-only study of 1,536 GWAS and candidate SNPs in African-Americans and European-Americans
[PMID 22733159] Analysis of prostate cancer association with four single-nucleotide polymorphisms from genome-wide studies and serum phyto-estrogen concentrations
[PMID 18794092] Association of prostate cancer risk variants with clinicopathologic characteristics of the disease.
[PMID 19104501] Prostate cancer genomics: towards a new understanding.
[PMID 19318432] Generalizability of associations from prostate cancer genome-wide association studies in multiple populations.
[PMID 19366831] Analysis of recently identified prostate cancer susceptibility loci in a population-based study: associations with family history and clinical features.
[PMID 19434657] Individual and cumulative effect of prostate cancer risk-associated variants on clinicopathologic variables in 5,895 prostate cancer patients.
[PMID 19549807] Prostate cancer risk associated loci in African Americans.
[PMID 19639606] Correcting "winner's curse" in odds ratios from genomewide association findings for major complex human diseases.
[PMID 20039378] Estimation of genotype relative risks from pedigree data by retrospective likelihoods.
[PMID 20690139] Meta-analysis of genome-wide and replication association studies on prostate cancer.
[PMID 21390317] Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3.
[PMID 21538423] Early onset prostate cancer has a significant genetic component.
