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From SNPedia

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ReferenceGRCh38 38.1/142
is asnp
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GWAS Ctlgrs187084
Max Magnitude
? (C;C) (C;T) (T;T) 28
[PMID 19505919OA-icon.png] Toll-like Receptor Signaling Pathway Variants and Prostate Cancer Mortality

[PMID 20422193] The investigation of toll-like receptor 3, 9 and 10 gene polymorphisms in Turkish rheumatoid arthritis patients

[PMID 21050493OA-icon.png] Toll-Like Receptor Gene Polymorphisms are Associated with Susceptibility to Graves' Ophthalmopathy in Taiwan Males

[PMID 21633947] Polymorphisms in the toll-like receptor 9 gene associated with sepsis and multiple organ dysfunction after major blunt trauma

[PMID 22041559] [The correlation between polymorphisms of Toll-like receptor 2 and Toll-like receptor 9 and susceptibility to gastric cancer]

[PMID 22594374OA-icon.png] Toll-like receptor 9 (TLR9) polymorphism associated with symptomatic malaria: a cohort study

[PMID 22714906OA-icon.png] Involvement of toll-like receptor 9 polymorphism in cervical cancer development

[PMID 18396467OA-icon.png] Genetic variation and haplotype structures of innate immunity genes in eastern India.

[PMID 18776126OA-icon.png] Toll-like receptor 9 affects severity of IgA nephropathy.

[PMID 19134200OA-icon.png] No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis.

[PMID 19284650OA-icon.png] TLR9 polymorphisms in African populations: no association with severe malaria, but evidence of cis-variants acting on gene expression.

[PMID 20137629] [Relationship between polymorphism sites of IRF5, TLR-9 and SLE patients in Shandong Han population].

[PMID 20227302] Polymorphisms in innate immunity genes associated with development of bronchiolitis obliterans after lung transplantation.

[PMID 20646321OA-icon.png] Toll-like receptor (TLR) and nucleosome-binding oligomerization domain (NOD) gene polymorphisms and endometrial cancer risk.

[PMID 21462132] [Association of single nucleotide polymorphisms in the promoter region of the TLR9 gene with childhood atopic asthma].

[PMID 21499878] Association of toll-like receptor 9 gene polymorphism in Chinese patients with systemic lupus erythematosus in Taiwan.

[PMID 21595536] Investigation of association between TLR9 gene polymorphisms and VKH in Japanese patients.

[PMID 21872627] Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.

[PMID 22059466] A genetic variant in the promoter region of Toll-like receptor 9 and cervical cancer susceptibility.

[PMID 22228476] Lack of association of Toll-like receptor 9 polymorphisms with susceptibility to systemic lupus erythematosus in an Asian population: a meta-analysis.

GET Evidence
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.414062

[PMID 22691414OA-icon.png] Role of polymorphisms of toll-like receptor (TLR) 4, TLR9, toll-interleukin 1 receptor domain containing adaptor protein (TIRAP) and FCGR2A genes in malaria susceptibility and severity in Burundian children

[PMID 22494793] Innate immunity gene single nucleotide polymorphisms and otitis media

[PMID 23420357] Meta-analysis demonstrates association between TLR polymorphisms and rheumatoid arthritis

[PMID 23021866OA-icon.png] Toll-like receptor gene variants associated with bacterial vaginosis among HIV-1 infected adolescents

[PMID 24004541] Association study of TLR-9 polymorphisms and systemic lupus erythematosus in Northern Chinese Han population

[PMID 24532514OA-icon.png] Single nucleotide polymorphisms of toll-like receptor 7 and toll-like receptor 9 in hepatitis C virus infection patients from central china

[PMID 22948541OA-icon.png] Contribution of toll-like receptor 9 gene single-nucleotide polymorphism to systemic lupus erythematosus.

[PMID 23161283OA-icon.png] SNPs in toll-like receptor (TLR) genes as new genetic alterations associated with congenital toxoplasmosis?

[PMID 23731219] Toll-like receptor-9 in Spanish multiple sclerosis patients: an association with the gender.

[PMID 23990988OA-icon.png] The TLR9 gene polymorphisms and the risk of cancer: evidence from a meta-analysis

[PMID 24971461OA-icon.png] Polymorphisms in the Inflammatory Pathway Genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG Are Associated with Susceptibility of Inflammatory Bowel Disease in a Danish Cohort

[PMID 25248338] The role of TLR9 polymorphism in susceptibility to pulmonary tuberculosis

[PMID 26270118] Gene Polymorphisms of Toll-Like Receptor 9 -1486T/C and 2848G/A in Cervical Cancer Risk

[PMID 24776844] Associations between functional polymorphisms in the NFκB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease

[PMID 26919710] Variations in genes involved in regulation of the nuclear factor - κB pathway and the risk of acute myeloid leukaemia.

[PMID 27105145OA-icon.png] TLR9 -1486T/C and 2848C/T SNPs Are Associated with Human Cytomegalovirus Infection in Infants.

[PMID 27432810] Genetic selection pressure in TLR9 gene may enforce risk for SLE in Indian Tamils.

[PMID 28703296] Correlation between TLR2, TLR3, TLR4, and TLR9 polymorphisms and susceptibility to and prognosis of severe hepatitis among the newborns.