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rs13042395

From SNPedia

Orientationplus
Stabilizedplus
Make rs13042395(C;C)
Make rs13042395(C;T)
Make rs13042395(T;T)
ReferenceGRCh38 38.1/141
Chromosome20
Position773867
GeneSLC52A3
is asnp
is mentioned by
dbSNPrs13042395
dbSNP (old)rs13042395
ClinGenrs13042395
ebirs13042395
HLIrs13042395
Exacrs13042395
Gnomadrs13042395
Varsomers13042395
Maprs13042395
PheGenIrs13042395
Biobankrs13042395
1000 genomesrs13042395
hgdprs13042395
ensemblrs13042395
gopubmedrs13042395
geneviewrs13042395
scholarrs13042395
googlers13042395
pharmgkbrs13042395
gwascentralrs13042395
openSNPrs13042395
23andMers13042395
23andMe allrs13042395
SNP Nexus

SNPshotrs13042395
SNPdbers13042395
MSV3drs13042395
GWAS Ctlgrs13042395
GMAF0.1249
Max Magnitude
? (C;C) (C;T) (T;T) 28
rs13042395 is a SNP in the C20orf54 gene.

In a large study of Han Chinese esophageal cancer patients [specifically esophageal squamous cell carcinoma (ESCC)], the rs13042395(T) allele was associated with lowered risk (odds ratio 0.86, p = 1.21 x 10e-11).[1]

In this same study [2], rs13042395(T) was also associated with lower risk for gastric cancer (aka stomach cancer), with an odds ratio of 0.91 (3 x 10e-3).

OMIM133239
Desc
Variant
Relatedalso
[PMID 22744421] Replication study of PLCE1 and C20orf54 polymorphism and risk of esophageal cancer in a Chinese population

[PMID 21427165OA-icon.png] Genetic variants at 1q22 and 10q23 reproducibly associated with gastric cancer susceptibility in a Chinese population.

[PMID 22037551] A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1.


[PMID 22805490OA-icon.png] Genetic variation in C20orf54, PLCE1 and MUC1 and the risk of upper gastrointestinal cancers in Caucasian populations.