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rs1109501

From SNPedia

Study: Archaic Hominid Introgression in Africa Contributes to Functional Salivary MUC7 Genetic Variation: "Here, we found that PTS-repeat copy number variation has evolved recurrently in the human lineage, thereby generating multiple haplotypic backgrounds carrying five or six PTS-repeat copy number alleles. Contrary to previous studies, we found no associations between the copy number of PTS-repeats and protection against asthma. Instead, we revealed a significant association of MUC7 haplotypic variation with the composition of the oral microbiome. Furthermore, based on in-depth simulations, we conclude that a divergent MUC7 haplotype likely originated in an unknown African hominin population and introgressed into ancestors of modern Africans."

The Guardian: "The secret about human evolution found in spit"


Orientationplus
Stabilizedplus
Make rs1109501(A;A)
Make rs1109501(A;G)
Make rs1109501(G;G)
ReferenceGRCh38 38.1/141
Chromosome4
Position70463773
GeneMUC7
is asnp
is mentioned by
dbSNPrs1109501
dbSNP (old)rs1109501
ClinGenrs1109501
ebirs1109501
HLIrs1109501
Exacrs1109501
Gnomadrs1109501
Varsomers1109501
Maprs1109501
PheGenIrs1109501
Biobankrs1109501
1000 genomesrs1109501
hgdprs1109501
ensemblrs1109501
gopubmedrs1109501
geneviewrs1109501
scholarrs1109501
googlers1109501
pharmgkbrs1109501
gwascentralrs1109501
openSNPrs1109501
23andMers1109501
23andMe allrs1109501
SNP Nexus

SNPshotrs1109501
SNPdbers1109501
MSV3drs1109501
GWAS Ctlgrs1109501
GMAF0.2631
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 21529783OA-icon.png]
Trait
Title A Quantitative-Trait Genome-Wide Association Study of Alcoholism Risk in the Community: Findings and Implications.
Risk Allele G
P-val 0.000005
Odds Ratio 0.1000 [NR] unit increase