Atorvastatin
From SNPedia
Atorvastatin is the chemical name for the statin drug marked under the brand names Lipitor.
Atorvastatin therapy is an example of a statin therapy that has been shown to substantially reduce the risk of coronary events in carriers of the risk allele for SNP rs20455.[PMID 18222353]
| Genotype/Genoset | Diplotype | Gene | Drug Use/Category/Class | Medical Field | Summary | Descriptive Sentence |
|---|---|---|---|---|---|---|
| rs7412(C;C) | non ApoE2 carrier | APOE | Statin | Cardiology | Consider Alternatives | You may have less of a response to atorvastatin (less reduction in LDL-cholesterol) compared to other genotypes for this variant. |
| rs7412(C;T) | E2 carrier (likely) | APOE | Statin | Cardiology | Normal Response Expected | You may have a better response to atorvastatin (greater reduction in LDL-cholesterol) compared to non-ApoE2 carriers. |
| rs7412(T;T) | E2/E2 (likely) | APOE | Statin | Cardiology | Normal Response Expected | You may have a better response to atorvastatin (greater reduction in LDL-cholesterol) compared to non-ApoE2 carriers. |
