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Amitriptyline

From SNPedia


A tricyclic antidepressant, this drug is used to treat depression and some other psychiatric conditions.

Trade names for amitriptyline include Elavil, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, Laroxyl.

Dosing recommendations from the CPIC indicate that CYP2D6 ultrarapid and poor metabolizers might wish to avoid amitriptyline use due to either reduced efficacy or more side effects, respectively.[1]

The following SNPs may influence a patient's response to this drug: