NOS3
From SNPedia
| is a | gene |
| is | mentioned by |
| Full name | nitric oxide synthase 3 (endothelial cell) |
| Other names | eNOS |
| Related | NOS1, NOS1AP, NOS2 |
| EntrezGene | 4846 |
| PheGenI | 4846 |
| VariationViewer | 4846 |
| ClinVar | NOS3 |
| GeneCards | NOS3 |
| dbSNP | 4846 |
| Diseases | NOS3 |
| SADR | 4846 |
| HugeNav | 4846 |
| wikipedia | NOS3 |
| NOS3 | |
| gopubmed | NOS3 |
| EVS | NOS3 |
| HEFalMp | NOS3 |
| MyGene2 | NOS3 |
| 23andMe | NOS3 |
| UniProt | P29474 |
| Ensembl | ENSG00000164867 |
| OMIM | 163729 |
| # SNPs | 19 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs11771443 | 0 | 150,990,599 | |
| rs1541861 | 0 | 151,000,245 | |
| rs1799983 | 0 | 150,999,023 | |
| rs1800779 | 0 | 150,992,855 | |
| rs1800780 | 0 | 151,001,791 | |
| rs1800783 | 0 | 150,992,309 | |
| rs1808593 | 0 | 151,011,214 | |
| rs2070744 | 2.1 | 150,992,991 | |
| rs2853792 | 0 | 151,002,789 | |
| rs2853796 | 0 | 151,006,827 | |
| rs3918181 | 0 | 151,004,695 | |
| rs3918188 | 0 | 151,005,693 | |
| rs3918226 | 0 | 150,993,088 | |
| rs3918227 | 0 | 151,003,858 | |
| rs4496877 | 1.2 | 150,983,418 | |
| rs743507 | 0 | 151,010,400 | |
| rs753482 | 0 | 151,009,295 | |
| rs7830 | 0 | 151,012,483 | |
| rs891512 | 3 | 151,011,001 |
NOS3 is also known as eNOS.
SNPs in NOS3 include:
- The promoter -786C/T SNP, rs2070744, implicated in:
- Rheumatoid Arthritis [PMID 17009241], and,
- cardiovascular mortality in high-risk patients [PMID 16979000]
- Progression (but not occurence) of prostate cancer [PMID 18823560]
- the Glu298Asp SNP, rs1799983, implicated in:
- ischemic heart disease
- an intron 4a SNP, implicated in:
- ischemic heart disease, [PMID 15007011]
- OR 1.34 (CI: 1.03-1.75); rs# TBD
- ischemic heart disease, [PMID 15007011]
