NOS1
From SNPedia
| is a | gene |
| is | mentioned by |
| Full name | nitric oxide synthase 1 (neuronal) |
| Related | NOS1AP, NOS2, NOS3 |
| EntrezGene | 4842 |
| PheGenI | 4842 |
| VariationViewer | 4842 |
| ClinVar | NOS1 |
| GeneCards | NOS1 |
| dbSNP | 4842 |
| Diseases | NOS1 |
| SADR | 4842 |
| HugeNav | 4842 |
| wikipedia | NOS1 |
| NOS1 | |
| gopubmed | NOS1 |
| EVS | NOS1 |
| HEFalMp | NOS1 |
| MyGene2 | NOS1 |
| 23andMe | NOS1 |
| UniProt | P29475 |
| Ensembl | ENSG00000089250 |
| OMIM | 163731 |
| # SNPs | 22 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs1004356 | 0 | 117,339,567 | |
| rs10507279 | 0 | 117,342,469 | |
| rs11611788 | 0 | 117,300,571 | |
| rs1483757 | 0 | 117,323,735 | |
| rs1520811 | 0 | 117,327,262 | |
| rs1879417 | 0 | 117,365,710 | |
| rs2139733 | 0 | 117,288,937 | |
| rs2293050 | 0 | 117,281,017 | |
| rs2682826 | 0 | 117,215,033 | |
| rs3782206 | 0 | 117,307,284 | |
| rs3782218 | 0 | 117,333,706 | |
| rs3782219 | 0 | 117,350,435 | |
| rs3782221 | 0 | 117,358,076 | |
| rs41279104 | 0 | 117,439,680 | |
| rs478597 | 0 | 117,313,620 | |
| rs561712 | 0 | 117,314,264 | |
| rs6490121 | 0 | 117,270,390 | |
| rs7308402 | 0 | 117,321,642 | |
| rs73208120 | 0 | 117,309,785 | |
| rs7977109 | 0 | 117,292,535 | |
| rs9658281 | 0 | 117,329,773 | |
| rs9658490 | 0 | 117,232,493 |
SNPs in the NOS1 gene, which is located on chromosome 12q, have been linked to restless legs syndrome. [PMID 18058820]
Examples of such SNPs include:
This finding may implicate the nitric oxide (NO)/arginine pathway in the development of restless legs syndrome, and thereby open the door to the use of NO modulating agents for its treatment. [PMID 18058820]
