From SNPedia
rs9858542 has been reported in a large study to be associated with
Crohn's disease.
The risk allele (oriented to the dbSNP entry) is (A); the odds ratio associated with heterozygotes is 1.09 (CI 0.96-1.24), and for homozygotes, 1.84 (CI 1.49-2.26). [PMID 17554300]
| ? | (A;A) (A;G) (G;G) |
|---|
 |
Related to INFLAMMATORY BOWEL DISEASE 12; IBD12
according to
omim 612241. See
also
| PharmGKB | PA162356661 |
| Name | |
| Annotation | GWAS Results: Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (Initial Sample Size: 1,748 cases, 2,938 controls; Replication Sample Size: (see Parkes 2007); Risk Allele: rs9858542-A). This variant is associated with crohn's disease. |
| Gene | BSN, APEH |
| Featue | |
| Evidence | PubMed ID:17554300; Web Resource:http://www.genome.gov/gwastudies/ |
| Drugs | |
| Diseases | Crohn Disease |
| Curation Level | Non-Curated |
[PMID 20024904] Variants at the 3p21 locus influence susceptibility and phenotype both in adults and early-onset patients with inflammatory bowel disease
| GWAS snp
|
| PMID
| [PMID 19915572]
|
| Trait
| Ulcerative colitis
|
| Title
| Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
|
| Risk Allele
|
|
| P-val
| 7E-9
|
| Odds Ratio
| NR NR
|
[PMID 19657358] Effect of BSN-MST1 locus on inflammatory bowel disease and multiple sclerosis susceptibility
