From SNPedia
rs9357271, a SNP located in the
BTBD9 gene region, has been linked to a lower frequency of
restless legs syndrome, a common sleep disorder, with an overall odds ratio of 0.63 (CI: 0.52-0.75) for the (C) minor allele. [
PMID 17637780]
This SNP may also be associated with Tourette syndrome (TS), particularly TS without obsessive-compulsive disorder, based on a study of ~600 patients.[PMID 19822783]
| ? | (C;C) (C;T) (T;T) |
|---|
 |
Related to RESTLESS LEGS SYNDROME, SUSCEPTIBILITY TO, 6
according to
omim 611185. See
also
| PharmGKB | PA162355628 |
| Name | |
| Annotation | In replicated GWAS case-control studies of Caucasian(European and French-Canadian) familial and sporadic RLS, the T allele of rs9357271 was significantly associated with Restless Legs Syndrome. |
| Gene | BTBD9 |
| Featue | |
| Evidence | PubMed ID:17637780 |
| Drugs | |
| Diseases | Restless Legs Syndrome |
| Curation Level | Curated |
