Rs806380
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs806380 |
| nextbio | rs806380 |
| hapmap | rs806380 |
| 1000 genomes | rs806380 |
| hgdp | rs806380 |
| ensembl | rs806380 |
| gopubmed | rs806380 |
| scholar | rs806380 |
| rs806380 | |
| pharmgkb | rs806380 |
| gwascentral | rs806380 |
| openSNP | rs806380 |
| 23andMe | rs806380 |
| 23andMe all | rs806380 |
| SNP Nexus | |
| SNPshot | rs806380 |
| SNPdbe | rs806380 |
| MSV3d | rs806380 |
| Gene | CNR1 |
| Chromosome | 6 |
| Orientation | plus |
| Position | 88864653 |
| Reference | GRCh37.p2 37.2/134 |
| Max Magnitude |
| Geno | Mag | Summary |
|---|---|---|
| (A;G) | ||
| (G;G) |
| Make rs806380(A;A) |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
This snp, located in intron 2 of the central cannabinoid receptor CNR1 gene, has been linked to cannabis dependence. [PMID 16917946]
The (G) allele is reported to have a protective effect, and is a defining part of a haplotype that is associated with lower odds of developing cannabis dependence. The (A) allele is more common in all populations studied.
[PMID 19443135] The association between cannabinoid receptor 1 gene (CNR1) and cannabis dependence symptoms in adolescents and young adults