Within the FTO gene, many SNPs appear to be co-inherited. The SNP showing the strongest association with body weight (i.e. body mass index, BMI) is not rs8043757, although this SNP is one of co-inherited SNPs in the FTO gene region. For more information, refer to the FTO gene or the most studied of FTO SNPs, rs9930506. [PMID 17658951]
[PMID 18379722] Variations in the FTO gene are associated with severe obesity in the Japanese.
|Title||Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.|
|Odds Ratio||1.23 [NR]|