rs80359734

plus

Geno	Mag	Summary
(-;GAGT)	6	BRCA2 variant considered pathogenic for breast cancer
(GAGT;GAGT)	0	common in clinvar
(TGAG;TGAG)	0	common in clinvar

Make rs80359734(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32379757

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359734
dbSNP (classic)	rs80359734
ClinGen	rs80359734
ebi	rs80359734
HLI	rs80359734
Exac	rs80359734
Gnomad	rs80359734
Varsome	rs80359734
LitVar	rs80359734
Map	rs80359734
PheGenI	rs80359734
Biobank	rs80359734
1000 genomes	rs80359734
hgdp	rs80359734
ensembl	rs80359734
geneview	rs80359734
scholar	rs80359734
google	rs80359734
pharmgkb	rs80359734
gwascentral	rs80359734
openSNP	rs80359734
23andMe	rs80359734
SNPshot	rs80359734
SNPdbe	rs80359734
MSV3d	rs80359734
GWAS Ctlg	rs80359734

Max Magnitude

6

rs80359734, also known as 9189del4, c.8961_8964delGAGT and p.Leu2987_Ser2988?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359734(-;-)
Alt	rs80359734(-;-)
Reference	Rs80359734(TGAG;TGAG)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer not provided Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 not provided Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32953894_32953897delGAGT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000045673.3, RCV000077457.5, RCV000215485.1, RCV000220005.1,