rs80359424

plus

Geno	Mag	Summary
(-;C)	6	BRCA2 variant considered pathogenic for breast cancer
(C;C)	0	common in clinvar

Make rs80359424(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32338431

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359424
dbSNP (classic)	rs80359424
ClinGen	rs80359424
ebi	rs80359424
HLI	rs80359424
Exac	rs80359424
Gnomad	rs80359424
Varsome	rs80359424
LitVar	rs80359424
Map	rs80359424
PheGenI	rs80359424
Biobank	rs80359424
1000 genomes	rs80359424
hgdp	rs80359424
ensembl	rs80359424
geneview	rs80359424
scholar	rs80359424
google	rs80359424
pharmgkb	rs80359424
gwascentral	rs80359424
openSNP	rs80359424
23andMe	rs80359424
SNPshot	rs80359424
SNPdbe	rs80359424
MSV3d	rs80359424
GWAS Ctlg	rs80359424

Max Magnitude

6

rs80359424, also known as 4304delC, c.4076_4076delC and p.Thr1359Metfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359424(-;-)
Alt	rs80359424(-;-)
Reference	Rs80359424(C;C)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2
Reversed	0
HGVS	NC_000013.10:g.32912568delC
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044341.2, RCV000113270.3,