rs80359304

plus

Geno	Mag	Summary
(-;TTAT)	6	BRCA2 variant considered pathogenic for breast cancer
(-;TTTA)	6	BRCA2 variant considered pathogenic for breast cancer
(TTTA;TTTA)	0	common in clinvar

Make rs80359304(-;-)

Reference

GRCh38 38.1/142

Chromosome

13

Position

32333250

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359304
dbSNP (classic)	rs80359304
ClinGen	rs80359304
ebi	rs80359304
HLI	rs80359304
Exac	rs80359304
Gnomad	rs80359304
Varsome	rs80359304
LitVar	rs80359304
Map	rs80359304
PheGenI	rs80359304
Biobank	rs80359304
1000 genomes	rs80359304
hgdp	rs80359304
ensembl	rs80359304
geneview	rs80359304
scholar	rs80359304
google	rs80359304
pharmgkb	rs80359304
gwascentral	rs80359304
openSNP	rs80359304
23andMe	rs80359304
SNPshot	rs80359304
SNPdbe	rs80359304
MSV3d	rs80359304
GWAS Ctlg	rs80359304

Merged from

Rs80359305

Max Magnitude

6

rs80359304, also known as c.1769_1772delTTAT, 2000del4, c.1772_1775delTTTA and p.Ile591_Tyr592?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359304(-;-) rs80359304(TTAT;TTAT)
Alt	rs80359304(-;-) rs80359304(TTAT;TTAT)
Reference	Rs80359304(TTTA;TTTA)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer Familial cancer of breast Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 Familial cancer of breast Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32907388_32907391delTTAT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000043880.4, RCV000112966.4, RCV000160268.1, RCV000213388.1,