rs80359025

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(A;C)	6	BRCA2 variant considered pathogenic for breast cancer
(C;C)	0	common in clinvar
(C;G)	6	BRCA2 variant considered pathogenic for breast cancer

Make rs80359025(G;G)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32362691

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359025
dbSNP (classic)	rs80359025
ClinGen	rs80359025
ebi	rs80359025
HLI	rs80359025
Exac	rs80359025
Gnomad	rs80359025
Varsome	rs80359025
LitVar	rs80359025
Map	rs80359025
PheGenI	rs80359025
Biobank	rs80359025
1000 genomes	rs80359025
hgdp	rs80359025
ensembl	rs80359025
geneview	rs80359025
scholar	rs80359025
google	rs80359025
pharmgkb	rs80359025
gwascentral	rs80359025
openSNP	rs80359025
23andMe	rs80359025
SNPshot	rs80359025
SNPdbe	rs80359025
MSV3d	rs80359025
GWAS Ctlg	rs80359025

Max Magnitude

6

rs80359025, also known as Y2658X, c.7974C>G and p.Tyr2658Ter, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359025(A;A) rs80359025(G;G)
Alt	rs80359025(A;A) rs80359025(G;G)
Reference	Rs80359025(C;C)
Significance	Pathogenic
Disease	Breast-ovarian cancer Familial cancer of breast
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Familial cancer of breast
Reversed	0
HGVS	NC_000013.10:g.32936828C>A; NC_000013.10:g.32936828C>G
CLNSRC	ClinVar
CLNACC	RCV000256889.2, RCV000031711.6, RCV000045360.2,