From SNPedia
| Geno
|
Mag
|
Summary
|
| (A;A)
|
2
|
1.5x higher risk for hypertension
|
| (A;C)
|
2
|
1.2x higher risk for hypertension
|
| (C;C)
|
0
|
normal
|
| ? | (A;A) (A;C) (C;C) | 28 |
|---|
 |
has been reported in a large study to be associated with
high blood pressure.
The risk allele (oriented to the dbSNP entry) is (A); the odds ratio associated with heterozygotes is 1.16 (CI 1.01-1.32), and for homozygotes, 1.47 (CI 1.25-1.74). [PMID 17554300]
This SNP was just about the only one tested to replicate as associated with hypertension in a study of 7,551 Koreans patients, with an odds ratio of 1.28 (CI: 1.012-1.636, p=0.04) but only in one of two cohorts.[PMID 19424278]
