| Geno
|
Mag
|
Summary
|
| (A;A)
|
|
CYP2C9*8 homozygote
|
| (A;G)
|
|
carrier of one CYP2C9*8 allele
|
| (G;G)
|
0
|
normal
|
rs7900194, also known as 449G>A, 3627G>A or R150H, is a SNP in the CYP2C9 gene.
The rs7900194(A) allele defines the CYP2C9*8 variant, which has decreased activity.
According to a 23andMe discussion This is one of the SNPs which were re-analyzed April 2009. Customers with older data may wish to redownload. SNPs effected rs4420638, rs34276300, rs3091244, rs34601266, rs2033003, rs7900194, rs9332239, rs28371685, rs1229984, and rs28399504.
[PMID 19663669] CYP2C9*8 is prevalent among African-Americans: implications for pharmacogenetic dosing.
| GET Evidence
|
| CYP2C9-R150H
|
| aa_change
|
Arg150His
|
| aa_change_short
|
R150H
|
| impact
|
pharmacogenetic
|
| qualified_impact
|
Insufficiently evaluated pharmacogenetic
|
| overall_frequency
|
0.0202715
|
| summary
|
|
