Rs7577363
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs7577363 |
| hapmap | rs7577363 |
| hgdp | rs7577363 |
| ensembl | rs7577363 |
| gopubmed | rs7577363 |
| scholar | rs7577363 |
| rs7577363 | |
| pharmgkb | rs7577363 |
| hgvbaseg2p | rs7577363 |
| medrefsnp | rs7577363 |
| 23andMe | rs7577363 |
| SNP Nexus |
| Gene | ALK |
| Chromosome | 2 |
| Orientation | plus |
| Position | 29729846 |
| Genotype | Effect |
|---|---|
| rs7577363(A;A) | >1.37x risk |
| rs7577363(A;G) | 1.37x risk |
| rs7577363(G;G) | common |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs7577363(A;A) | >1.37x risk | |
| Rs7577363(A;G) | 1.37x risk | |
| Rs7577363(C;C) | 00 | |
| Rs7577363(G;G) | 00 | common |
rs7577363 has been reported in a large study to be associated with multiple sclerosis.
The risk allele (oriented to the dbSNP entry) is (A); the odds ratio associated with this allele is 1.37 (CI 1.17-1.61). [PMID 17660530]
| ? | (A;A) (A;G) (G;G) |
|---|---|
|
| |
| PharmGKB | PA162356165 |
| Name | |
| Annotation | In a replicated GWAS of U.K. and U.S. case/parent trios, this variant was shown to be associated with multiple sclerosis risk. |
| Gene | ALK |
| Featue | |
| Evidence | PubMed ID:17660530 |
| Drugs | |
| Diseases | Multiple Sclerosis |
| Curation Level | Curated |
