Rs7183877

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is asnp
is mentioned by
dbSNPrs7183877
hapmaprs7183877
hgdprs7183877
ensemblrs7183877
gopubmedrs7183877
scholarrs7183877
googlers7183877
pharmgkbrs7183877
hgvbaseg2prs7183877
medrefsnprs7183877
23andMers7183877
SNP Nexus

GeneOCA2
Chromosome15
Orientationplus
Position26039327
GenotypeEffect
rs7183877(A;A)usually brown eye color
rs7183877(A;C)usually brown eye color
rs7183877(C;C)blue eye color if part of blue eye color haplotype


Genotypes Magnitude Summary
Rs7183877(A;A) usually brown eye color
Rs7183877(A;C) usually brown eye color
Rs7183877(C;C) blue eye color if part of blue eye color haplotype
rs7183877 is part of a haplotype spanning 166kB on chromosome 15, defined by 13 SNPs listed below, found in 97% of all Caucasians with blue eyes. In this haplotype, variations in rs1129038 and rs12913832 are relatively common in Caucasians though rare among other ethnic groups.[PMID 18172690]

The "h-1" haplotype found in homozygous state in 97% of individuals with blue eye color is composed as follows [PMID 18172690]:

rs4778241(C)
rs1129038(A)
rs12593929(A)
rs12913832(G)
rs7183877(C)
rs3935591(G)
rs7170852(A)
rs2238289(T)
rs3940272(C)
rs8028689(T)
rs2240203(A)
rs11631797(G)
rs916977(G)

? (A;A) (A;C) (C;C)
Neighborrs12913832
Distance115