From SNPedia
| Geno
|
Mag
|
Summary
|
| (G;G)
|
2
|
1.5x higher risk for hypertension
|
| (G;T)
|
2
|
1.2x higher risk for hypertension
|
| (T;T)
|
0
|
normal
|
| ? | (G;G) (G;T) (T;T) | 28 |
 |
rs6997709 has been reported in a large study to be associated with
high blood pressure.
The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.20 (CI 0.94-1.52), and for homozygotes, 1.49 (CI 1.18-1.89). [PMID 17554300]
In a study of 7,551 Koreans, this SNP was associated with systolic and diastolic blood pressures in a quantitative trait association test but no associations were found using a case-control association test.[PMID 19424278]