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Rs688034

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Orientationplus
is asnp
is mentioned by
dbSNPrs688034
PheGenIrs688034
nextbiors688034
hapmaprs688034
1000 genomesrs688034
hgdprs688034
ensemblrs688034
gopubmedrs688034
geneviewrs688034
scholarrs688034
googlers688034
pharmgkbrs688034
gwascentralrs688034
openSNPrs688034
23andMers688034
23andMe allrs688034
SNP Nexus

SNPshotrs688034
SNPdbers688034
MSV3drs688034
GeneSEZ6L
Chromosome22
Orientationplus
GMAF0.1602
Position26293669
ReferenceGRCh38 38.1/141
Max Magnitude2
Geno Mag Summary
(C;C) 0 normal
(C;T) 1.1 1.1x risk higher risk for coronary artery disease
(T;T) 2 1.6x risk
? (C;C) (C;T) (T;T) 28
rs688034 has been reported in a large study to be associated with heart disease, in particular, coronary artery disease.

The risk allele (oriented to the dbSNP entry) is (T); the odds ratio associated with heterozygotes is 1.11 (CI 0.98-1.25), and for homozygotes, 1.62 (CI 1.34-1.95). [PMID 17554300OA-icon.png]

GWAS
SNP rs688034
PubMedID [PMID 17554300OA-icon.png]
Condition Coronary disease
Gene NR
Risk Allele T
pValue 4.00E-006
OR 1.11
95% CI 0.99-1.25



[PMID 19956433OA-icon.png] Genetics of coronary artery disease: focus on genome-wide association studies.


[PMID 20017983OA-icon.png] Evaluation of population impact of candidate polymorphisms for coronary heart disease in the Framingham Heart Study Offspring Cohort.


GET Evidence
rs688034
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.140625
summary