From SNPedia
| ? | (A;A) (A;G) (G;G) | 28 |
|---|
 |
| GWAS snp
|
| PMID
|
[PMID 18823527]
|
| Trait
|
Alzheimer's disease
|
| Title
|
A genome-wide association study for late-onset Alzheimer's disease using DNA pooling
|
| Risk Allele
|
A
|
| P-val
|
5.9999999999999997E-14
|
| Odds Ratio
|
NR NR
|
| PharmGKB | PA164740849 |
| Name | |
| Annotation | GWAS results: A genome-wide association study for late-onset Alzheimer's disease using DNA pooling. (Initial Sample Size: 1,082 cases, 1,239 controls; Replication Sample Size: 1,400 additional controls); (Region: 19q13.32; Reported Gene(s): PVRL2, TOMM40, APOE; Risk Allele: rs6859-A); (p-value= 5.99999999999999E-14).This variant is associated with Alzheimer's disease. |
| Gene | PVRL2 |
| Featue | |
| Evidence | PubMed ID:18823527; Web Resource:http://www.genome.gov/gwastudies/ |
| Drugs | |
| Diseases | Alzheimer Disease |
| Curation Level | Non-Curated |
The risk allele associated with late-onset Alzheimer's disease is A. [PMID 18823527]
| GWAS snp
|
| PMID
|
[PMID 20885792]
|
| Trait
|
|
| Title
|
Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities
|
| Risk Allele
|
A
|
| P-val
|
1E-7
|
| Odds Ratio
|
1.41 [1.24-1.60]
|
| GWAS snp
|
| PMID
|
[PMID 22159054]
|
| Trait
|
|
| Title
|
A comprehensive genetic association study of Alzheimer disease in African Americans.
|
| Risk Allele
|
A
|
| P-val
|
5E-7
|
| Odds Ratio
|
1.5800 None
|
