Rs6682654

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is asnp
is mentioned by
dbSNPrs6682654
hapmaprs6682654
hgdprs6682654
ensemblrs6682654
gopubmedrs6682654
scholarrs6682654
googlers6682654
pharmgkbrs6682654
hgvbaseg2prs6682654
medrefsnprs6682654
23andMers6682654
SNP Nexus

GeneCD244
Chromosome1
Orientationplus
Position159075626
GenotypeEffect
rs6682654(A;A)normal
rs6682654(A;G)1.34x increased risk for rheumatoid arthritis
rs6682654(G;G)1.8x increased risk for rheumatoid arthritis


Genotypes Magnitude Summary
Rs6682654(A;A) normal
Rs6682654(A;G) 1.34x increased risk for rheumatoid arthritis
Rs6682654(G;G) 1.8x increased risk for rheumatoid arthritis
Two SNPs on ch 1q in the CD244 gene, rs3766379 and rs6682654, were found to be associated with risk for rheumatoid arthritis in two independent Japanese cohorts (p = 3.23 x 10e-8) and p = 7.45 x 10e-8). The odds ratio reported for the more common rs6682654(G) allele, as oriented in dbSNP and not the publication, was 1.34 (CI: 1.15-1.55, p = 0.0002).[PMID 18794858]
? (A;A) (A;G) (G;G)
Related to RHEUMATOID ARTHRITIS; RA according to omim 180300. See also
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