Rs6604026
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs6604026 |
| hapmap | rs6604026 |
| hgdp | rs6604026 |
| ensembl | rs6604026 |
| gopubmed | rs6604026 |
| scholar | rs6604026 |
| rs6604026 | |
| pharmgkb | rs6604026 |
| hgvbaseg2p | rs6604026 |
| medrefsnp | rs6604026 |
| 23andMe | rs6604026 |
| SNP Nexus |
| Gene | RPL5 |
| Chromosome | 1 |
| Orientation | plus |
| Position | 93076190 |
| Genotype | Effect |
|---|---|
| rs6604026(C;C) | >1.15x risk |
| rs6604026(C;T) | 1.15x risk |
| rs6604026(T;T) | common |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs6604026(C;C) | 22 | >1.15x risk |
| Rs6604026(C;T) | 1.15x risk | |
| Rs6604026(T;T) | 00 | common |
The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with this allele is 1.15 (CI 1.08-1.22). [PMID 17660530]
| ? | (C;C) (C;T) (T;T) |
|---|---|
|
| |
| GWAS | |
|---|---|
| SNP | rs6604026 |
| PubMedID | [PMID 17660530] |
| Condition | Multiple sclerosis |
| Gene | RPL5 |
| Risk Allele | C |
| pValue | 8.00E-006 |
| OR | 1.15 |
| 95% CI | 1.08-1.22 |
| GWAS snp | |
|---|---|
| PMID | [PMID 19525955] |
| Trait | Multiple sclerosis |
| Title | Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20 |
| Risk Allele | G |
| P-val | 0.000003 |
| Odds Ratio | 1.17 [NR] |
[PMID 18650830] Replication of KIAA0350, IL2RA, RPL5 and CD58 as multiple sclerosis susceptibility genes in Australians
| PharmGKB | PA162356162 |
| Name | |
| Annotation | In a replicated GWAS of U.K. and U.S. case/parent trios, this variant was shown to be associated with multiple sclerosis risk. |
| Gene | SNORA66, RPL5, SNORD21, FAM69A |
| Featue | |
| Evidence | PubMed ID:17660530 |
| Drugs | |
| Diseases | Multiple Sclerosis |
| Curation Level | Curated |
