Rs657152

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Gene

Chromosome

9

minus

Position

136139265

Reference

GRCh37 37.1/131

?	(G;G) (G;T) (T;T)	28

GWAS snp
PMID	[PMID 18940312]
Trait	Plasma levels of liver enzymes
Title	Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes
Risk Allele	T
P-val	2E-30
Odds Ratio	0.05 [0.039-0.055] U/L decrease

The T allele of this SNP is associated with higher risk of pancreatic cancer. [PMID 19648918]

OMIM	171720
Desc	ALKALINE PHOSPHATASE, PLASMA LEVEL OF, QUANTITATIVE TRAIT LOCUS 1
Variant
Related	also

PharmGKB	PA164740809
Name
Annotation	GWAS results: Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. (Initial Sample Size: 7,751 European white individuals; Replication Sample Size: 4,704 European white and Indian Asian individua); (Region: 9p34.2; Reported Gene(s): ABO; Risk Allele: rs657152-T); (p-value= 2E-30).This variant is associated with Plasma levels of liver enzymes.
Gene	ABO
Featue
Evidence	PubMed ID:18940312; Web Resource:http://www.genome.gov/gwastudies/
Drugs
Diseases
Curation Level	Non-Curated

[PMID 20529992] Genetic Regulation of Serum Phytosterol Levels and Risk of Coronary Artery Disease