Rs6495306

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Orientationplus
is asnp
is mentioned by
dbSNPrs6495306
PheGenIrs6495306
nextbiors6495306
hapmaprs6495306
1000 genomesrs6495306
hgdprs6495306
ensemblrs6495306
gopubmedrs6495306
geneviewrs6495306
scholarrs6495306
googlers6495306
pharmgkbrs6495306
gwascentralrs6495306
openSNPrs6495306
23andMers6495306
23andMe allrs6495306
SNP Nexus

SNPshotrs6495306
SNPdbers6495306
MSV3drs6495306
GeneCHRNA5
Chromosome15
Orientationplus
GMAF0.2764
Position78865893
ReferenceGRCh37 37.1/131
Max Magnitude2
Geno Mag Summary
(G;G) 2
Make rs6495306(A;A)
Make rs6495306(A;G)
? (A;A) (A;G) (G;G) 28
Rs6495306
PubMed [PMID 18414406]
Affy Probeset SNP_A-8603150
Affy Orientation reverse
On GW 5.0
Alleles A/B C/T
Ancestral A
Population mixed
Allele G
Case Freq.
Control Freq.
Odds Ratio Het
Odds Ratio Hom
Odds Ratio All 1.43
Disease Substance dependence, Alcohol (SD-A)


rs6495306 increases susceptibility to Substance dependence, Alcohol 1.43 times for carriers of the G allele [PMID 18414406]


[PMID 19064933OA-icon.png] Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans.


[PMID 19443489OA-icon.png] Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.


[PMID 19706762OA-icon.png] The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.