rs6220
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(G;G) | 0 | common in clinvar |
Make rs6220(A;A) |
Make rs6220(A;G) |
Reference | GRCh38 38.1/141 |
Chromosome | 12 |
Position | 102400737 |
Gene | IGF1, LOC105369942 |
is a | snp |
is | mentioned by |
dbSNP | rs6220 |
dbSNP (classic) | rs6220 |
ClinGen | rs6220 |
ebi | rs6220 |
HLI | rs6220 |
Exac | rs6220 |
Gnomad | rs6220 |
Varsome | rs6220 |
LitVar | rs6220 |
Map | rs6220 |
PheGenI | rs6220 |
Biobank | rs6220 |
1000 genomes | rs6220 |
hgdp | rs6220 |
ensembl | rs6220 |
geneview | rs6220 |
scholar | rs6220 |
rs6220 | |
pharmgkb | rs6220 |
gwascentral | rs6220 |
openSNP | rs6220 |
23andMe | rs6220 |
SNPshot | rs6220 |
SNPdbe | rs6220 |
MSV3d | rs6220 |
GWAS Ctlg | rs6220 |
GMAF | 0.3526 |
Max Magnitude | 0 |
[PMID 17911177] Implications for prostate cancer of IGF1 the TCC haplotype and the rs6220 SNP were associated with elevated levels of circulating IGF1 (p = 0.001 and <0.0001, respectively)
[PMID 19784788] Association of IGF1 and IGFBP3 polymorphisms with colorectal polyps and colorectal cancer risk
[PMID 21552154] Common genetic variation in the IGF1 associates with maximal force output
[PMID 18064566] Common genetic variation in the IGF-1 gene, serum IGF-I levels and breast density.
[PMID 18199734] IGF-I and IGF-II genetic variation and breast cancer risk in Chinese women: results from the Shanghai Breast Cancer Study.
[PMID 18398029] Genetic polymorphisms involved in insulin-like growth factor (IGF) pathway in relation to mammographic breast density and IGF levels.
[PMID 18562769] Genetic variation in insulin-like growth factors and brain tumor risk.
[PMID 18772892] Can genes for mammographic density inform cancer aetiology?
[PMID 20302654] Genotypes and haplotypes in the insulin-like growth factors, their receptors and binding proteins in relation to plasma metabolic levels and mammographic density.
[PMID 21113804] IGF1 htSNPs in relation to IGF-1 levels in young women from high-risk breast cancer families: implications for early-onset breast cancer.
[PMID 21791631] Pharmacogenetic angiogenesis profiling for first-line Bevacizumab plus oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer.
[PMID 23180020] Association of a common genetic variant of the IGF-1 gene with event-free survival in patients with HER2-positive breast cancer
[PMID 23530598] Insulin-like growth factor-1 genotypes and haplotypes influence the survival of prostate cancer patients with bone metastasis at initial diagnosis
[PMID 28315227] Insulin-like growth factor 1 gene polymorphism in women with breast cancer.
ClinVar | |
---|---|
Risk | rs6220(A;A) |
Alt | rs6220(A;A) |
Reference | Rs6220(G;G) |
Significance | Non-pathogenic |
Disease | Insulin-like growth factor I deficiency |
Variation | info |
Gene | IGF1 |
CLNDBN | Insulin-like growth factor I deficiency |
Reversed | 0 |
HGVS | NC_000012.11:g.102794515G>A |
CLNSRC | |
CLNACC | RCV000348790.1, |
[PMID 29172265] SNPs in the Insulin-Like Growth Factor Gene and Obesity Impact on Colorectal Cancer in Egyptians