Rs602662

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Orientationplus
is asnp
is mentioned by
dbSNPrs602662
PheGenIrs602662
hapmaprs602662
1000 genomesrs602662
hgdprs602662
ensemblrs602662
gopubmedrs602662
geneviewrs602662
scholarrs602662
googlers602662
pharmgkbrs602662
gwascentralrs602662
openSNPrs602662
23andMers602662
23andMe allrs602662
SNP Nexus

SNPshotrs602662
SNPdbers602662
MSV3drs602662
GeneFUT2
Chromosome19
Orientationplus
GMAF0.3375
Position48703728
ReferenceGRCh38 38.1/141
Max Magnitude
Make rs602662(A;A)
Make rs602662(A;G)
Make rs602662(G;G)
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 19303062OA-icon.png]
Trait Folate pathway vitamins
Title Genome-wide Association Study of Vitamin B6, Vitamin B12, Folate, and Homocysteine Blood Concentrations
Risk Allele A
P-val 3E-20
Odds Ratio 49.77 [37.09-62.45] pg/ml increase
OMIM612542
DescVITAMIN B12 PLASMA LEVEL QUANTITATIVE TRAIT LOCUS 1; B12QTL1
Variant
Relatedalso
[PMID 19744961OA-icon.png] Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway


OMIM182100
Desc
Variant
Relatedalso
[PMID 18776911OA-icon.png] Common variants of FUT2 are associated with plasma vitamin B12 levels.


[PMID 18997004OA-icon.png] Widespread balancing selection and pathogen-driven selection at blood group antigen genes.


[PMID 20570966OA-icon.png] Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.


[PMID 21115529OA-icon.png] Genetics and genomics of human ageing.


GET Evidence
FUT2-G258S
aa_change Gly258Ser
aa_change_short G258S
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.508645
summary



[PMID 22521342OA-icon.png] Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci.


[PMID 23201895] Common variant in FUT2 gene is associated with levels of vitamin B(12) in Indian population.