| ? | (A;A) (A;G) (G;G) | 28 |
|---|
 |
| GWAS snp
|
| PMID
|
[PMID 19303062]
|
| Trait
|
Folate pathway vitamins
|
| Title
|
Genome-wide Association Study of Vitamin B6, Vitamin B12, Folate, and Homocysteine Blood Concentrations
|
| Risk Allele
|
A
|
| P-val
|
3E-20
|
| Odds Ratio
|
49.77 [37.09-62.45] pg/ml increase
|
| OMIM | 612542 |
| Desc | VITAMIN B12 PLASMA LEVEL QUANTITATIVE TRAIT LOCUS 1; B12QTL1 |
| Variant | |
| Related | also |
[PMID 19744961] Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway
[PMID 18776911] Common variants of FUT2 are associated with plasma vitamin B12 levels.
[PMID 18997004] Widespread balancing selection and pathogen-driven selection at blood group antigen genes.
[PMID 20570966] Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.
[PMID 21115529] Genetics and genomics of human ageing.
| GET Evidence
|
| FUT2-G258S
|
| aa_change
|
Gly258Ser
|
| aa_change_short
|
G258S
|
| impact
|
pharmacogenetic
|
| qualified_impact
|
Insufficiently evaluated pharmacogenetic
|
| overall_frequency
|
0.508645
|
| summary
|
|
