Rs5839491

Orientation

plus

is a	snp
is	mentioned by
dbSNP	rs5839491
PheGenI	rs5839491
nextbio	rs5839491
hapmap	rs5839491
1000 genomes	rs5839491
hgdp	rs5839491
ensembl	rs5839491
gopubmed	rs5839491
geneview	rs5839491
scholar	rs5839491
google	rs5839491
pharmgkb	rs5839491
gwascentral	rs5839491
openSNP	rs5839491
23andMe	rs5839491
23andMe all	rs5839491
SNP Nexus
SNPshot	rs5839491
SNPdbe	rs5839491
MSV3d	rs5839491

Gene	UGT1A1, UGT1A3, UGT1A4, UGT1A5, UGT1A6, UGT1A7, UGT1A8, UGT1A9, UGT1A10

Chromosome

2

Orientation

plus

Position

234668885

Reference

GRCh37.p2 37.2/134

Max Magnitude

Geno	Mag	Summary
(-;-)		normal risk
(-;AT)		some effects of higher bilirubin
(AT;AT)		effects of higher bilirubin; irinotecan toxicity

rs5839491 is one of four SNPs all describing an insertion/deletion polymorphism in the promoter region of the UGT1A1 gene; the primary entry in SNPedia for this set of SNPs is at rs34815109.

The other two SNPs (besides rs34815109) that also describe the same polymorphism are:

• rs35600288
• rs34983651

Neighbor	rs34815109
Distance	5

Neighbor	rs35600288
Distance	1

[PMID 20528568] Evaluation of UGT1A1 and SULT1A1 polymorphisms with lipid levels in women with different hormonal status.