From SNPedia
| Geno
|
Mag
|
Summary
|
| (A;A)
|
0
|
normal
|
| (A;G)
|
|
0.5x reduced risk for asthma
|
| (G;G)
|
|
0.5x reduced risk for asthma
|
| ? | (A;A) (A;G) (G;G) | 28 |
|---|
 |
is a SNP in the natriuretic peptide precursor A
NPPA gene.
In a study of ~500 asthma patients, rs5067(G) were at reduced (50% or 76%) risk; the odds ratio in the first and second populations were 0.5 (CI: 0.29-0.84, p=0.009) and 0.24 (CI: 0.11-0.53, p<0.0001), respectively. The population-attributable risk for asthma in carriers of the rs5067(G) allele was 23.3%.[PMID 18294255]
