From SNPedia
rs4958847 is a SNP in the IRGM gene.
A study of 507 CD patients, 475 UC patients and 576 controls from New Zealand Caucasians found that rs4958847, a SNP in the IRGM gene, was associated specifically with ileal Crohn's disease but not with other forms of inflammatory bowel disease. The reported odds ratio was 1.767, CI: 1.224-2.558, p=0.0022.[PMID 18580884]
Another study, including 557 Crohn's disease (CD) patients, 425 ulcerative colitis (UC) patients, and 672 ethnically matched Spanish controls as well as a meta-analysis concluded that rs4958847(A) was associated with CD (p=2.78 x 10(-17), pooled odds ratio 1.31) and UC (p=0.014, pooled odds ratio 1.13).[PMID 19491842]
| ? | (A;A) (A;G) (G;G) |
|---|
 |
[PMID 19174780] Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort
Related to INFLAMMATORY BOWEL DISEASE 19; IBD19
according to
omim 612278. See
also
Related to IMMUNITY-RELATED GTPase FAMILY, M; IRGM
according to
omim 608212. See
also
