rs4763655
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | >1.10x risk | |
| (A;G) | 1.10x risk | |
| (G;G) | 0 | common |
| Reference | GRCh38 38.1/141 |
| Chromosome | 12 |
| Position | 9602982 |
| Gene | KLRB1, LOC107987174 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4763655 |
| dbSNP (classic) | rs4763655 |
| ClinGen | rs4763655 |
| ebi | rs4763655 |
| HLI | rs4763655 |
| Exac | rs4763655 |
| Gnomad | rs4763655 |
| Varsome | rs4763655 |
| LitVar | rs4763655 |
| Map | rs4763655 |
| PheGenI | rs4763655 |
| Biobank | rs4763655 |
| 1000 genomes | rs4763655 |
| hgdp | rs4763655 |
| ensembl | rs4763655 |
| geneview | rs4763655 |
| scholar | rs4763655 |
| rs4763655 | |
| pharmgkb | rs4763655 |
| gwascentral | rs4763655 |
| openSNP | rs4763655 |
| 23andMe | rs4763655 |
| SNPshot | rs4763655 |
| SNPdbe | rs4763655 |
| MSV3d | rs4763655 |
| GWAS Ctlg | rs4763655 |
| GMAF | 0.343 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs4763655 has been reported in a large study to be associated with multiple sclerosis.
The risk allele (oriented to the dbSNP entry) is (A); the odds ratio associated with this allele is 1.10 (CI 1.04-1.17). [PMID 17660530]
[PMID 21610746
] Alterations in KLRB1 gene expression and a Scandinavian multiple sclerosis association study of the KLRB1 SNP rs4763655
[PMID 22492128] Association of SNPs rs6498169 and rs10984447 with multiple sclerosis in Saudi patients: a model of the usefulness of familial aggregates in identifying genetic linkage in a multifactorial disease.
