From SNPedia
rs4415084 and rs10941679 confer risk for estrogen receptor breast cancer (ER)-positive tumors (OR = 1.27, P = 2.5E-12 for rs10941679) based on a study of 6,145 cases. [PMID 18438407] From a DeCode user report, the risk allele appears to be T; this T;T individual reportedly has a 1.19x increased risk of breast cancer.
| ? | (C;C) (C;T) (T;T) |
|---|
 |
| PharmGKB | PA162355813 |
| Name | |
| Annotation | This variant is associated with risk for estrogen receptor (ER)-positive breast cancer. |
| Gene | - |
| Featue | |
| Evidence | PubMed ID:18438407 |
| Drugs | |
| Diseases | Breast Neoplasms |
| Curation Level | Curated |
[PMID 20095854] Novel Breast Cancer Risk Alleles and Interaction with Ionizing Radiation among U.S. Radiologic Technologists
[PMID 20140701] Genetic variants on chromosome 5p12 are associated with risk of breast cancer in African American women: the Black Women's Health Study
