Rs419788

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is asnp
is mentioned by
dbSNPrs419788
hapmaprs419788
hgdprs419788
ensemblrs419788
gopubmedrs419788
scholarrs419788
googlers419788
pharmgkbrs419788
hgvbaseg2prs419788
medrefsnprs419788
23andMers419788
SNP Nexus

GeneSKIV2L
Chromosome6
Orientationminus
Position32036777
GenotypeEffect
rs419788(A;A)2.3x risk for lupus
rs419788(A;G)2.0x risk for lupus
rs419788(G;G)average


Genotypes Magnitude Summary
Rs419788(A;A) 2.3x risk for lupus
Rs419788(A;G) 2.0x risk for lupus
Rs419788(G;G) 00 average
rs419788, a SNP in an intron of the SKIV2L gene in the MHC class III region, has been associated with lupus in a large study of UK patients. In dbSNP orientation, the risk allele is rs419788(A), and the risk is dose-dependent (i.e. rs419788(A;A) individuals are at higher risk than rs419788(A;G) individuals]. The reported odds ratio is 2.0 (CI: 1.6 - 2.6, permuted p < 0.0001). [PMID 17997607]
? (A;A) (A;G) (G;G)
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