Rs3890745
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs3890745 |
| hapmap | rs3890745 |
| hgdp | rs3890745 |
| ensembl | rs3890745 |
| gopubmed | rs3890745 |
| scholar | rs3890745 |
| rs3890745 | |
| pharmgkb | rs3890745 |
| hgvbaseg2p | rs3890745 |
| medrefsnp | rs3890745 |
| 23andMe | rs3890745 |
| SNP Nexus |
| Gene | MMEL1 |
| Chromosome | 1 |
| Orientation | minus |
| Position | 2553624 |
| Reference | GRCh37 37.1/131 |
| Genotype | Effect |
|---|---|
| rs3890745(A;A) | 1.12x risk of Rheumatoid arthritis |
| rs3890745(A;G) | |
| rs3890745(G;G) | normal |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs3890745(A;A) | 1.12x risk of Rheumatoid arthritis | |
| Rs3890745(A;G) | ||
| Rs3890745(G;G) | 00 | normal |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
| GWAS | |
|---|---|
| SNP | rs3890745 |
| PubMedID | [PMID 18794853] |
| Condition | Rheumatoid arthritis |
| Gene | MMEL1-TNFRSF14 |
| Risk Allele | T |
| pValue | 1.00E-007 |
| OR | 1.12 |
| 95% CI | |
Related to RHEUMATOID ARTHRITIS; RA
according to omim 180300. See also
| PharmGKB | PA162356418 |
| Name | |
| Annotation | GWAS Results: Common variants at CD40 and other loci confer risk of rheumatoid arthritis (Initial Sample Size: 3,393 cases, 12,460 controls; Replication Sample Size: 3,929 cases, 5,807 controls; Risk Allele: rs3890745-T). This variant is associated with Rheumatoid arthritis. |
| Gene | MMEL1 |
| Featue | |
| Evidence | PubMed ID:18794853; Web Resource:http://www.genome.gov/gwastudies/ |
| Drugs | |
| Diseases | Arthritis, Rheumatoid |
| Curation Level | Non-Curated |
| GWAS snp | |
|---|---|
| PMID | [PMID 20453842] |
| Trait | Rheumatoid arthritis |
| Title | Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk lock |
| Risk Allele | T |
| P-val | 0.000004 |
| Odds Ratio | 1.12 [1.06-1.18] |
