Rs3865418
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs3865418 |
| hapmap | rs3865418 |
| hgdp | rs3865418 |
| ensembl | rs3865418 |
| gopubmed | rs3865418 |
| scholar | rs3865418 |
| rs3865418 | |
| pharmgkb | rs3865418 |
| hgvbaseg2p | rs3865418 |
| medrefsnp | rs3865418 |
| 23andMe | rs3865418 |
| SNP Nexus |
| Gene | NEDD4L |
| Chromosome | 18 |
| Orientation | plus |
| Position | 54155143 |
| Genotype | Effect |
|---|---|
| rs3865418(C;C) | normal |
| rs3865418(C;T) | 1.3x increased risk for hypertension |
| rs3865418(T;T) | >1.3x increased risk for hypertension |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs3865418(C;C) | 00 | normal |
| Rs3865418(C;T) | 1.3x increased risk for hypertension | |
| Rs3865418(G;G) | 00 | |
| Rs3865418(T;T) | >1.3x increased risk for hypertension |
Association under an additive model yielded an odds ratio of 1.31 (CI: 1.04-1.67, p=0.025) for the rs3865418(T) allele. The association remained significant (p = 0.039) after adjusting for age and sex, and was primarily associated with significantly higher diastolic blood pressure.[PMID 18293164]
| ? | (C;C) (C;T) (T;T) |
|---|---|
|
| |
