Rs3816587

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is asnp
is mentioned by
dbSNPrs3816587
hapmaprs3816587
hgdprs3816587
ensemblrs3816587
gopubmedrs3816587
scholarrs3816587
googlers3816587
pharmgkbrs3816587
hgvbaseg2prs3816587
medrefsnprs3816587
23andMers3816587
SNP Nexus

GeneANAPC4
Chromosome4
Orientationplus
Position25026341
GenotypeEffect
rs3816587(C;C)1.3x risk
rs3816587(C;T)normal
rs3816587(T;T)normal


Genotypes Magnitude Summary
Rs3816587(C;C) 1.3x risk
Rs3816587(C;T) 00 normal
Rs3816587(T;T) 00 normal

rs3816587 has been reported in a large study to be associated with rheumatoid arthritis.

The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with heterozygotes is 0.91 (CI 0.80-1.04), and for homozygotes, 1.35 (CI 1.14-1.59). [PMID 17554300]

? (C;C) (C;T) (T;T)
GWAS
SNP rs3816587
PubMedID [PMID 17554300]
Condition Rheumatoid arthritis
Gene NR
Risk Allele C
pValue 9.00E-006
OR 1.09
95% CI 0.96-1.25


PharmGKBPA162356653
Name
AnnotationGWAS Results: Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (Initial Sample Size: 1,860 cases, 2,938 controls; Replication Sample Size: NR; Risk Allele: rs3816587-C). This variant is associated with rheumatoid arthritis.
GeneANAPC4
Featue
EvidencePubMed ID:17554300; Web Resource:http://www.genome.gov/gwastudies/
Drugs
DiseasesArthritis, Rheumatoid
Curation LevelNon-Curated