From SNPedia
rs3802842 is a SNP in a region of ch 11q23.1 that has been associated with some cancers.
IN a study of over 10,000 cases of colorectal cancer, rs3802842(C) was associated with increased risk (odds ratio 1.17, CI: 1.12-1.22, p = 1.08 x 10e-12). Additional SNPs in chromosomal regions 8q21, 8q24, 10p14, 11q, 15q13.3 and 18q21 can be combined additively to produce an overall risk, with an average odds ratio per risk allele of 1.19.[PMID 18753146]
| ? | (A;A) (A;C) (C;C) |
|---|
 |
Related to COLORECTAL CANCER, SUSCEPTIBILITY TO, 7; CRCS7
according to
omim 612232. See
also
[PMID 19843678] Enrichment of Low Penetrance Susceptibility Loci in a Dutch Familial Colorectal Cancer Cohort
| PharmGKB | PA162356761 |
| Name | |
| Annotation | GWAS Results: Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21 (Initial Sample Size: 981 cases, 1,002 controls; Replication Sample Size: 16,476 cases, 15,351 controls; Risk Allele: rs3802842-C). |
| Gene | C11orf92 |
| Featue | |
| Evidence | PubMed ID:18372901; Web Resource:http://www.genome.gov/gwastudies/ |
| Drugs | |
| Diseases | Colorectal Neoplasms |
| Curation Level | Non-Curated |
