From SNPedia
Testicular germ cell tumor risk I("TGCT"; i.e.
testicular cancer risk) was increased 3x per copy of the major (T) allele at
rs3782179 and
rs4474514 (OR = 3.08, CI: 2.29–4.13; OR = 3.07, CI = 2.29–4.13, respectively), based on a genome-wide scan of 277 primarily Caucasian TGCT cases and 919 controls. Men who have two copies of the common version of the c-KIT ligand
KITLG gene have a 4.5-fold higher risk of testicular cancer than men who have two copies of the less common or minor version of the gene. [
PMID 19483682]
| ? | (C;C) (C;T) (T;T) |
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