Rs3782179

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is asnp
is mentioned by
dbSNPrs3782179
hapmaprs3782179
hgdprs3782179
ensemblrs3782179
gopubmedrs3782179
scholarrs3782179
googlers3782179
pharmgkbrs3782179
hgvbaseg2prs3782179
medrefsnprs3782179
23andMers3782179
SNP Nexus

Chromosome12
Orientationplus
Position87477456
GenotypeEffect
rs3782179(C;C)
rs3782179(C;T)3x increased testicular cancer risk for men
rs3782179(T;T)


Genotypes Magnitude Summary
Rs3782179(C;C)
Rs3782179(C;T) 3x increased testicular cancer risk for men
Rs3782179(T;T)
Testicular germ cell tumor risk I("TGCT"; i.e. testicular cancer risk) was increased 3x per copy of the major (T) allele at rs3782179 and rs4474514 (OR = 3.08, CI: 2.29–4.13; OR = 3.07, CI = 2.29–4.13, respectively), based on a genome-wide scan of 277 primarily Caucasian TGCT cases and 919 controls. Men who have two copies of the common version of the c-KIT ligand KITLG gene have a 4.5-fold higher risk of testicular cancer than men who have two copies of the less common or minor version of the gene. [PMID 19483682]
? (C;C) (C;T) (T;T)