rs3781719
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 2x increased hypertension risk | |
| (C;T) | 2x increased hypertension risk | |
| (T;T) | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 11 |
| Position | 14972978 |
| Gene | CALCA |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3781719 |
| dbSNP (classic) | rs3781719 |
| ClinGen | rs3781719 |
| ebi | rs3781719 |
| HLI | rs3781719 |
| Exac | rs3781719 |
| Gnomad | rs3781719 |
| Varsome | rs3781719 |
| LitVar | rs3781719 |
| Map | rs3781719 |
| PheGenI | rs3781719 |
| Biobank | rs3781719 |
| 1000 genomes | rs3781719 |
| hgdp | rs3781719 |
| ensembl | rs3781719 |
| geneview | rs3781719 |
| scholar | rs3781719 |
| rs3781719 | |
| pharmgkb | rs3781719 |
| gwascentral | rs3781719 |
| openSNP | rs3781719 |
| 23andMe | rs3781719 |
| SNPshot | rs3781719 |
| SNPdbe | rs3781719 |
| MSV3d | rs3781719 |
| GWAS Ctlg | rs3781719 |
| GMAF | 0.3145 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs3781719 is a SNP, also known as T-692C, in the calcitonin-related polypeptide alpha CALCA gene.
A study of 293 Chinese subjects with essential hypertension (EH) and 208 controls concluded that rs3781719(C) allele carriers were associated with increased EH risk (odds ratio 2.093, CI: 1.317-3.326, p<0.01).[PMID 18959118]
[PMID 23237777] Association study of the calcitonin gene-related polypeptide-alpha (CALCA) and the receptor activity modifying 1 (RAMP1) genes with migraine.
