From SNPedia
| Geno
|
Mag
|
Summary
|
| (C;C)
|
1.1
|
increased risk of parkinson's disease
|
| (C;T)
|
0
|
normal risk of parkinson's disease
|
| (T;T)
|
0
|
normal risk of parkinson's disease
|
| ? | (C;C) (C;T) (T;T) | 28 |
|---|
 |
CC linked to
parkinson's disease
[PMID 17905480] We provide evidence for a novel, strong and reproducible association of the PITX3 promoter SNP rs3758549 : C>T (p=0.004) with PD. The C-allele appears to be a recessive risk allele with an estimated population frequency of 83%.
[PMID 19345444] Association of transcription factor polymorphisms PITX3 and EN1 with Parkinson's disease.
[PMID 21138504] The transcription factor Pitx3 is a risk modifier for Parkinson's disease in a Chinese Han population
[PMID 21524731] PITX3 gene polymorphism is associated with Parkinson's disease in Chinese population
[PMID 21565251] Genetic variants of the PITX3 gene are not associated with late-onset sporadic Parkinson's disease in a Chinese population
[PMID 22411443] A novel synonymous SNP in PITX3 is associated with Parkinson's disease in Chinese population
