Rs3758549
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs3758549 |
| hapmap | rs3758549 |
| hgdp | rs3758549 |
| ensembl | rs3758549 |
| gopubmed | rs3758549 |
| scholar | rs3758549 |
| rs3758549 | |
| pharmgkb | rs3758549 |
| hgvbaseg2p | rs3758549 |
| medrefsnp | rs3758549 |
| 23andMe | rs3758549 |
| SNP Nexus |
| Gene | PITX3 |
| Chromosome | 10 |
| Orientation | minus |
| Position | 103994185 |
| Genotype | Effect |
|---|---|
| rs3758549(C;C) | increased risk of parkinson's disease |
| rs3758549(C;T) | normal risk of parkinson's disease |
| rs3758549(T;T) | normal risk of parkinson's disease |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs3758549(C;C) | 1.11.1 | increased risk of parkinson's disease |
| Rs3758549(C;T) | 00 | normal risk of parkinson's disease |
| Rs3758549(T;T) | 00 | normal risk of parkinson's disease |
[PMID 17905480] We provide evidence for a novel, strong and reproducible association of the PITX3 promoter SNP rs3758549 : C>T (p=0.004) with PD. The C-allele appears to be a recessive risk allele with an estimated population frequency of 83%.
| ? | (C;C) (C;T) (T;T) |
|---|---|
|
| |
[PMID 19345444] Association of transcription factor polymorphisms PITX3 and EN1 with Parkinson's disease.
