From SNPedia
| Geno
|
Mag
|
Summary
|
| (A;A)
|
2
|
lower HDL cholesterol
|
| (A;G)
|
|
lower HDL cholesterol
|
| (G;G)
|
|
normal risk
|
| ? | (A;A) (A;G) (G;G) | 28 |
|---|
 |
The (A) allele of rs326 was associated with risk for lower high-density lipoprotein (HDL) cholesterol plasma levels in 3 independent population samples, including both Caucasians and African-Americans.[PMID 17952847]
| GWAS snp
|
| PMID
|
[PMID 18193046]
|
| Trait
|
Triglycerides
|
| Title
|
Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides
|
| Risk Allele
|
A
|
| P-val
|
4.9999999999999997E-12
|
| Odds Ratio
|
6.60 [3.66-9.54] % higher
|
| PharmGKB | PA161613798 |
| Name | |
| Annotation | This SNP has been associated with small changes in HDL cholesterol levels. The A allele has been correlated with lower HDL. |
| Gene | LPL |
| Featue | |
| Evidence | PubMed ID:17952847 |
| Drugs | |
| Diseases | |
| Curation Level | Curated |
[PMID 21149302] Effects of genetic variants on lipid parameters and dyslipidemia in a Chinese population
