Rs326

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is asnp
is mentioned by
dbSNPrs326
hapmaprs326
hgdprs326
ensemblrs326
gopubmedrs326
scholarrs326
googlers326
pharmgkbrs326
hgvbaseg2prs326
medrefsnprs326
23andMers326
SNP Nexus

GeneLPL
Chromosome8
Orientationplus
Position19863718
GenotypeEffect
rs326(A;A)lower HDL cholesterol
rs326(A;G)lower HDL cholesterol
rs326(G;G)normal risk


Genotypes Magnitude Summary
Rs326(A;A) 22 lower HDL cholesterol
Rs326(A;G) lower HDL cholesterol
Rs326(G;G) normal risk

The (A) allele of rs326 was associated with risk for lower high-density lipoprotein (HDL) cholesterol plasma levels in 3 independent population samples, including both Caucasians and African-Americans.[PMID 17952847]

? (A;A) (A;G) (G;G)
GWAS snp
PMID [PMID 18193046]
Trait Triglycerides
Title Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides
Risk Allele A
P-val 4.9999999999999997E-12
Odds Ratio 6.60 [3.66-9.54] % higher
Related to LIPOPROTEIN LIPASE; LPL according to omim 609708. See also


PharmGKBPA161613798
Name
AnnotationThis SNP has been associated with small changes in HDL cholesterol levels. The A allele has been correlated with lower HDL.
GeneLPL
Featue
EvidencePubMed ID:17952847
Drugs
Diseases
Curation LevelCurated