From SNPedia
| Geno
|
Mag
|
Summary
|
| (C;C)
|
0
|
better response to certain calcium channel blockers
|
| (C;T)
|
0
|
normal
|
| (T;T)
|
|
normal
|
| ? | (C;C) (C;T) (T;T) | 28 |
|---|
 |
is a SNP in the calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1D gene.
A study of 161 Japanese patients (85 men, 76 women) being treated for hypertension with L-type dCCBs (calcium channel blockers) concluded that individuals with rs312481(C;C) genotypes responded better, as measured by lowered systolic and diastolic blood pressure readings.[PMID 19225208]
