Rs3025786
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs3025786 |
| hapmap | rs3025786 |
| hgdp | rs3025786 |
| ensembl | rs3025786 |
| gopubmed | rs3025786 |
| scholar | rs3025786 |
| rs3025786 | |
| pharmgkb | rs3025786 |
| hgvbaseg2p | rs3025786 |
| medrefsnp | rs3025786 |
| 23andMe | rs3025786 |
| SNP Nexus |
| Gene | PSEN1 |
| Chromosome | 14 |
| Orientation | plus |
| Position | 72734470 |
| Genotype | Effect |
|---|---|
| rs3025786(C;C) | slightly decreased Alzheimer's disease risk among ApoE4 carriers |
| rs3025786(C;T) | slightly decreased Alzheimer's disease risk among ApoE4 carriers |
| rs3025786(T;T) | normal |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs3025786(C;C) | slightly decreased Alzheimer's disease risk among ApoE4 carriers | |
| Rs3025786(C;T) | slightly decreased Alzheimer's disease risk among ApoE4 carriers | |
| Rs3025786(T;T) | normal |
rs3025786 is a SNP in the presenilin 1 PSEN1 gene.
A study of a Spanish case-control sample of 1,183 individuals showed rs3025786 was associated with Alzheimer's disease in an ApoE-specific manner: more specifically rs3025786(C) allele carriers have a decreased AD risk among carriers of the ApoE4 allele. [PMID 18957849]
