|(C;T)||2||2.6x increased risk for ARMD in a Taiwanese population|
|(T;T)||2||2.6x increased risk for ARMD in a Taiwanese population|
A study of 190 Taiwanese patients with late wet age related macular degeneration found that the rs3025039(T) allele was associated with increased risk, with an odds ratio of 2.61 (CI: 1.68 to 4.07, p = 1.45 x 10e-5).[PMID 18378209]
Note that this association may be completely due to the tight linkage (D' = 0.99) between this SNP and rs1061170, which has been reported by numerous studies to be associated with ARMD.
[PMID 19594543] Effect of vascular endothelial growth factor polymorphisms on survival in advanced-stage non-small-cell lung cancer
[PMID 19875757] Clinical relevance of vascular endothelial growth factor (VEGFA) and VEGF receptor (VEGFR2) gene polymorphism on the treatment outcome following imatinib therapy
[PMID 20082870] A Single Nucleotide Polymorphism in the Vascular Endothelial Growth Factor Gene Is Associated with Recurrence of Hepatocellular Carcinoma after Transplantation
[PMID 20847577] Vascular Endothelial Growth Factor Gene Polymorphisms and Risk of Neovascular Age-Related Macular Degeneration in a Chinese Cohort
C->T was associated with increased risk for altitude sickness. [PMID 21242666] Polymorphisms of Hypoxia-Related Genes in Subjects Susceptible to Acute Mountain Sickness
[PMID 22129133] VEGFA and VEGFR2 genetic polymorphisms and survival in patients with diffuse large B cell lymphoma
[PMID 22315135] The single-nucleotide polymorphisms +936 C/T VEGF and -710 C/T VEGFR1 are associated with breast cancer protection in a Spanish population
[PMID 22439647] The outcome and predictive factors of sunitinib therapy in advanced gastrointestinal stromal tumors (GIST) after imatinib failure - one institution study
[PMID 22162628] Polymorphisms in the vascular endothelial growth factor gene and the risk of diabetic retinopathy in Chinese patients with type 2 diabetes
[PMID 21905000] Disruption of vascular homeostasis in Kawasaki Disease patients: Involvement of vascular endothelial growth factor and angiopoietins.
[PMID 22818823] Association of VEGF-A genetic polymorphisms with cancer risk and survival in advanced-stage oral squamous cell carcinoma patients
[PMID 15338501] Vascular endothelial growth factor gene polymorphisms in Behcet's disease.
[PMID 16613616] Polymorphisms in the vascular endothelial growth factor gene and breast cancer in the Cancer Prevention Study II cohort.
[PMID 16645995] Vascular endothelial growth factor gene haplotypes in Kawasaki disease.
[PMID 17204151] VEGF, FGF1, FGF2 and EGF gene polymorphisms and psoriatic arthritis.
[PMID 17319747] Large-scale evaluation of candidate genes identifies associations between VEGF polymorphisms and bladder cancer risk.
[PMID 17601350] A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.
[PMID 17983459] Vascular endothelial growth factor (VEGF) gene (VEGFA) polymorphism can predict the prognosis in acute myeloid leukaemia patients.
[PMID 18281657] VEGF polymorphisms and survival in early-stage non-small-cell lung cancer.
[PMID 18650217] Polymorphisms in the vascular endothelial growth factor gene and the risk of familial endometriosis.
[PMID 18676870] Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China.
[PMID 18780893] Genetic polymorphisms of VEGF, interactions with cigarette smoking exposure and esophageal adenocarcinoma risk.
[PMID 18805939] Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis.
[PMID 19041064] Vascular endothelial growth factor gene polymorphisms may predict the risk of acute graft-versus-host disease following allogeneic transplantation: preventive effect of vascular endothelial growth factor gene on acute graft-versus-host disease.
[PMID 19089753] Variation in the vascular endothelial growth factor gene, carotid intima-media thickness and the risk of acute myocardial infarction.
[PMID 19196101] Combinational polymorphisms of seven CXCL12-related genes are protective against breast cancer in Taiwan.
[PMID 19372140] EGFR pathway polymorphisms and bladder cancer susceptibility and prognosis.
[PMID 19438866] Polymorphisms in genes involved in DNA repair, cell growth, oxidative stress and inflammatory response, and melanoma risk.
[PMID 19496079] Effect of polymorphisms in the 3' untranslated region (3'-UTR) of vascular endothelial growth factor gene on gastric cancer and peptic ulcer diseases in Japan.
[PMID 19566948] Polymorphisms of TGFB1 and VEGF genes and survival of patients with gastric cancer.
[PMID 19584152] Vascular endothelial growth factor polymorphisms and esophageal cancer prognosis.
[PMID 19603096] An analysis of growth, differentiation and apoptosis genes with risk of renal cancer.
[PMID 19628492] Polymorphism of the manganese superoxide dismutase gene but not of vascular endothelial growth factor gene is a risk factor for diabetic retinopathy.
[PMID 19755511] The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors.
[PMID 19787077] Association of vascular endothelial growth factor polymorphisms with asthma in Tunisian children.
[PMID 19835575] The VEGF -634G>C promoter polymorphism is associated with risk of gastric cancer.
[PMID 20019880] Polymorphisms in the VEGFA and VEGFR-2 genes and neovascular age-related macular degeneration.
[PMID 20389299] Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism.
[PMID 20540786] The association of 18F-deoxyglucose (FDG) uptake of PET with polymorphisms in the glucose transporter gene (SLC2A1) and hypoxia-related genes (HIF1A, VEGFA, APEX1) in non-small cell lung cancer. SLC2A1 polymorphisms and FDG-PET in NSCLC patients.
[PMID 21080079] Gene polymorphism of vascular endothelial growth factor -1154 G>A is associated with hypertensive nephropathy in a Hispanic population.
[PMID 21245770] Vascular endothelial growth factor gene polymorphisms and rheumatoid arthritis.
[PMID 21347390] Genetics of VEGF serum variation in human isolated populations of cilento: importance of VEGF polymorphisms.
[PMID 21362767] Interaction between smoking and polymorphism in the promoter region of the VEGFA gene is associated with ischemic heart disease and myocardial infarction in rheumatoid arthritis.
[PMID 21982816] Contribution of VEGF polymorphisms to variation in VEGF serum levels in a healthy population.
[PMID 22139971] Vascular endothelial growth factor (VEGF) gene polymorphisms may influence the efficacy of thalidomide in multiple myeloma.
[PMID 22320189] Polymorphisms of the vascular endothelial growth factor gene and severe radiation pneumonitis in non-small cell lung cancer patients treated with definitive radiotherapy.
[PMID 22429695] Polymorphism in the vascular endothelial growth factor A (VEGFA) gene is associated with serum VEGF-A level and disease activity in rheumatoid arthritis: differential effect of cigarette smoking.
[PMID 22521084] Role of Vascular Endothelial Growth Factor Polymorphisms in the Treatment Success in Patients with Wet Age-related Macular Degeneration.
[PMID 23073296] VEGF Polymorphisms are not associated with an Increased Risk of Developing Renal Cell Carcinoma in Spanish population
[PMID 23211130] Polymorphisms in the vascular endothelial growth factor gene associated with recurrent spontaneous miscarriage
[PMID 22776467] Age at onset of rheumatoid arthritis: association with polymorphisms in the vascular endothelial growth factor A(VEGFA) gene and an intergenic locus between matrix metalloproteinase (MMP) 1 and 3 genes
[PMID 23631762] Genotyping analysis and 18FDG uptake in breast cancer patients: a preliminary research
[PMID 23848209] Vascular endothelial growth factor A (VEGFA) polymorphisms in Chinese patients with rheumatoid arthritis
[PMID 23880405] Methionine sulfoxide reductase A rs10903323 G/A polymorphism is associated with increased risk of coronary artery disease in a Chinese population
[PMID 24353087] Assessment of the associations between three VEGF polymorphisms and risk of prostate cancer
[PMID 22491902] The interaction between the maternal BMI and angiogenic gene polymorphisms associates with the risk of spontaneous preterm birth.
[PMID 22729570] AKT3, ANGPTL4, eNOS3, and VEGFA associations with high altitude sickness in Han and Tibetan Chinese at the Qinghai-Tibetan Plateau.
[PMID 22925497] The relation of vascular endothelial growth factor (VEGF) gene polymorphisms on VEGF levels and the risk of vasoocclusive crisis in sickle cell disease.
[PMID 23061744] Association of the vascular endothelial growth factor gene polymorphisms (-460C/T, +405G/C and +936T/C) with endometriosis: a meta-analysis.
[PMID 23102494] Vascular endothelial growth factor family gene polymorphisms in preeclampsia in Sinhalese women in Sri-Lanka.
[PMID 23264084] Positive association of the vascular endothelial growth factor-A +405 GG genotype and poor survival in stage I-II gastric cancer in the Northern Chinese population.
[PMID 23545315] Further evidence for the contribution of the vascular endothelial growth factor gene in coronary artery disease susceptibility.
[PMID 23586368] Vascular endothelial growth factor 936 c>T polymorphism increased oral cancer risk: evidence from a meta-analysis.
[PMID 23625573] A common and functional gene variant in the vascular endothelial growth factor a predicts clinical outcome in early-stage breast cancer.
[PMID 23644986] Genetic polymorphisms of vascular endothelial growth factor and risk for retinopathy of prematurity in South of Iran.
[PMID 24868559] The Associations between VEGF Gene Polymorphisms and Diabetic Retinopathy Susceptibility: A Meta-Analysis of 11 Case-Control Studies
[PMID 24940484] Association between vascular endothelial growth factor gene polymorphisms and bladder cancer risk
[PMID 25713884] Serum cytokine levels in patients with colorectal cancers according to tumor stages and VEGF gene polymorphism
[PMID 25894981] Genetic Variations of VEGF Gene Were Associated with Tetralogy of Fallot Risk in a Chinese Han Population
[PMID 26075076] Involvement of vascular endothelial growth factor -460 C/T, +405 G/C and +936 C/T polymorphisms in the development of endometriosis
[PMID 26264619] Vascular endothelial growth factor polymorphisms and a synchronized examination of plasma and tissue expression in epithelial ovarian cancers
[PMID 24971577] Vascular endothelial growth factor A (VEGFA) gene polymorphisms have an impact on survival in a subgroup of indolent patients with chronic lymphocytic leukemia
[PMID 25714003] Association of VEGFA gene polymorphisms and VEGFA plasma levels with spontaneous preterm birth
[PMID 27116510] Effect of Risk Alleles in CFH, C3, and VEGFA on the Response to Intravitreal Bevacizumab in Tunisian Patients with Neovascular Age-related Macular Degeneration.