Rs2987983
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs2987983 |
| hapmap | rs2987983 |
| hgdp | rs2987983 |
| ensembl | rs2987983 |
| gopubmed | rs2987983 |
| scholar | rs2987983 |
| rs2987983 | |
| pharmgkb | rs2987983 |
| hgvbaseg2p | rs2987983 |
| medrefsnp | rs2987983 |
| 23andMe | rs2987983 |
| SNP Nexus |
| Gene | ESR2 |
| Chromosome | 14 |
| Orientation | minus |
| Position | 63833405 |
| Genotype | Effect |
|---|---|
| rs2987983(C;C) | 1.2x increased risk of prostate cancer |
| rs2987983(C;T) | 1.2x increased risk of prostate cancer |
| rs2987983(T;T) | normal risk |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs2987983(C;C) | 1.2x increased risk of prostate cancer | |
| Rs2987983(C;T) | 22 | 1.2x increased risk of prostate cancer |
| Rs2987983(T;T) | 00 | normal risk |
[PMID 16921512] In one large Swedish study, men with one or two rs2987983(C) alleles were reported to be at somewhat increased (odds ratio 1.22) risk for Prostate cancer compared to men homozygous for the wild type rs2987983(T) allele, however the risk can be reduced by adding phytoestrogens to the diet.
| ? | (C;C) (C;T) (T;T) |
|---|---|
|
| |
[PMID 19429453] Polymorphisms in the promoter region of ESR2 gene and breast cancer susceptibility
Related to ESTROGEN RECEPTOR 2; ESR2
according to omim 601663. See also
| PharmGKB | PA161145070 |
| Name | ESR2:rs2987983 |
| Annotation | Haplotype tagging SNP. |
| Gene | ESR2 |
| Featue | |
| Evidence | PubMed ID:17579196 |
| Drugs | |
| Diseases | |
| Curation Level | Curated |
