| Li-Fraumeni syndrome?? (an inherited cancer predisposition - but see note below) |
| Geno
|
Mag
|
Summary
|
| (A;A)
|
8
|
info@snpedia.com would like to hear from you
|
| (A;G)
|
4
|
Li-Fraumeni syndrome?? (an inherited cancer predisposition - but see note below)
|
| (G;G)
|
0
|
common in clinvar
|
This genotype is associated with Li Fraumeni syndrome. However, we have noticed a statistically unlikely increase in the number of customers of one DNA testing company who's genotype for this SNP is being incorrectly reported. This is likely to be a technical error - you probably actually carry the completely normal, unmutated genotype for this SNP. You should seek to have a clinically validated test carried out if you have either a significant family history of cancer or if you have any concerns about this.
See https://www.reddit.com/r/23andme/comments/2xit8m/how_does_one_interpret_significance/
