Rs2837960

From SNPedia

Jump to: navigation, search
is asnp
is mentioned by
dbSNPrs2837960
hapmaprs2837960
hgdprs2837960
ensemblrs2837960
gopubmedrs2837960
scholarrs2837960
googlers2837960
pharmgkbrs2837960
hgvbaseg2prs2837960
medrefsnprs2837960
23andMers2837960
SNP Nexus

Chromosome21
Orientationplus
Position41433787
GenotypeEffect
rs2837960(G;G)2.3x risk
rs2837960(G;T)normal
rs2837960(T;T)normal


Genotypes Magnitude Summary
Rs2837960(G;G) 2.3x risk
Rs2837960(G;T) 00 normal
Rs2837960(T;T) 00 normal

rs2837960 has been reported in a large study to be associated with rheumatoid arthritis.

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 0.95 (CI 0.83-1.08), and for homozygotes, 2.30 (CI 1.64-3.23). [PMID 17554300]

? (G;G) (G;T) (T;T)
GWAS
SNP rs2837960
PubMedID [PMID 17554300]
Condition Rheumatoid arthritis
Gene NR
Risk Allele G
pValue 2.00E-006
OR 1.05
95% CI 0.93-1.20


PharmGKBPA162356650
Name
AnnotationGWAS Results: Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (Initial Sample Size: 1,860 cases, 2,938 controls; Replication Sample Size: NR; Risk Allele: rs2837960-G). This variant is associated with Rheumatoid arthritis.
Gene-
Featue
EvidencePubMed ID:17554300; Web Resource:http://www.genome.gov/gwastudies/
Drugs
DiseasesArthritis, Rheumatoid
Curation LevelNon-Curated