Rs28371706
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs28371706 |
| hapmap | rs28371706 |
| hgdp | rs28371706 |
| ensembl | rs28371706 |
| gopubmed | rs28371706 |
| scholar | rs28371706 |
| rs28371706 | |
| pharmgkb | rs28371706 |
| hgvbaseg2p | rs28371706 |
| medrefsnp | rs28371706 |
| 23andMe | rs28371706 |
| SNP Nexus |
| Gene | CYP2D6 |
| Chromosome | 22 |
| Orientation | minus |
| Position | 40855715 |
| Genotype | Effect |
|---|---|
| rs28371706(T;T) | CYP2D6*17 homozygote |
| rs28371706(C;T) | carrier of one CYP2D6*17 allele |
| rs28371706(C;C) | normal |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs28371706(C;C) | 00 | normal |
| Rs28371706(C;T) | carrier of one CYP2D6*17 allele | |
| Rs28371706(G;G) | 00 | |
| Rs28371706(T;T) | CYP2D6*17 homozygote |
rs28371706, also known as 1023C>T or T107I, is a SNP in the CYP2D6 gene.
The rs28371706(T) allele defines the CYP2D6*17 variant, which has decreased activity.
| PharmGKB | PA161145191 |
| Name | CYP2D6:1023 C>T |
| Annotation | Variant was identified as being part of the reduced function haplotype CYP2D6*17. |
| Gene | CYP2D6 |
| Featue | Exon/NonSyn |
| Evidence | Web Resource:http://www.pharmgkb.org/search/annotatedGene/cyp2d6/variant.jsp#ImportantVariantInformationforCYP2D6-222 |
| Drugs | |
| Diseases | |
| Curation Level | In-Depth |
